Optimal control aspects of left ventricular ejection dynamics.
نویسنده
چکیده
A model of the ejecting left ventricle is developed in which ventricular elastance as a function of time is optimized with respect to a simple performance index selected on an energetic basis. The model correctly predicts a number of well known experimental findings concerning the effects of preload and afterload conditions and varying system parameters on left ventricular pressure and elastance waveforms and on the ejection period. The results characterize ventricular systolic elastance as dependent on both end-diastolic volume and mean aortic pressure.
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عنوان ژورنال:
- Journal of theoretical biology
دوره 63 2 شماره
صفحات -
تاریخ انتشار 1976